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Advantage® II

Advantage II eliminates fleas and lice and now offers better protection for your dog. A highly effective pest treatment, the formula is for dogs and puppies older than 7 weeks and weighing over 55 lbs. Advantage II is also safe and will not harm pregnant or nursing dogs.

This flea control product eliminates fleas at all of their life stages. The fast-acting formula imidacloprid will kill fleas within 12 hours and re-infesting fleas within 2 hours.

Advantage II eliminates fleas and lice by killing their eggs and larvae completely with an integrated flea control (IFC) solution. Using properties like adulticidal, larvicidal, and ovicidal, the new and improved Advantage II formula inhibits flea growth. Specifically targeting insects, pyriproxyfen uses hormone signaling to stop insects from developing during their maturity cycle.


  • Prevent fleas from infesting your home, kills fleas at all life stages
  • Uses imidacloprid which paralyzes fleas, kills on contact, and reduces flea allergy
  • Waterproof
  • Guaranteed US EPA approved
  • Quick and easy application with easy-squeeze tube
  • Long lasting topical, 4 or 6 months per package

Dog products use Advantage II monthly to kill fleas on your dog quickly. The active ingredient, imidacloprid, acts on the nervous system of the flea to cause paralysis and subsequent death.


Advantage® II Small Dog


Advantage® II Medium Dog


Advantage® II Large Dog


Advantage® II Extra Large Dog

Advantage II flea treatment for cats has been redesigned and improved, enhancing the protections this cat flea treatment offers. Advantage II is among the best flea treatment for cats. Advantage flea medicine only has to be applied one time per month, and it will provide a full 30-day protection from fleas and their eggs or larvae.


Advantage® II Kitten


Advantage® II Small Cats


Advantage® II Large Cat

Q1: How long does it take to kill all fleas after first application on an animal that has fleas?

A: 24 hours to zero fleas counted.

Q2: Does it kill ticks as well as fleas?

A: No, there is no tick activity at all. This product is highly specific for fleas.

Q3: Activity against parasites other than fleas and ticks?

A: Fleas only.

Q4: How long does a single application last?

A: One month.

Q5: How soon after bathing can it be applied?

A: As soon as the pet is dry.

Q6: Does it wash off?

A: Yes - this product will be washed off completely with a degreasing shampoo. It can withstand one bath between applications and swimming once a week between applications but no more.

Q7: Flea killing active ingredient:

A: Imidocloprid

Q8: How young can the pet be for application?

A: Puppies - 7 weeks, kittens - 8 weeks

Q9: Approved for use in pregnant or nursing mother dogs/cats?

A: not in this country but in other countries yes (U.S. EPA does not recognize testing done for other countries and testing in pregnancy/lactation has not been done in the U.S.)

Q10: Does the pet need a veterinarian office call in the last year to get the product?

A: No, this is an insecticide, not a drug, but the manufacturer sells its product for resale only through veterinarians so that proper usage etc. can be explained.

Q11: Is the product safe for use on sick, elderly or debilitated patients?

A: Product should be safe for such use provided the patient is receiving veterinary care. Otherwise, if the pet is inactive or hospitalized in a cage, the product may not spread around the body as rapidly as usual.